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Who was studied at least 20,352 European ancestry cases, at least 31,358 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.0916 higher (95% confidence interval 0.063-0.12); p = 4 × 10−10.
How common The T allele had a frequency of about 83% in the people studied.
Where it sits Chromosome 1, band 1q21.2 — between genes, 18.9 kb from OTUD7B.
What each result means
C/CNo copy of the version the research linked to Bipolar disorder (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Bipolar disorder (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Bipolar disorder (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Translational psychiatry · 2021 · PMID 33479212 · open access
Questions about rs72692857
What is rs72692857?
rs72692857 is a single position in the genome, in or near the near OTUD7B gene. Published research associates it with bipolar disorder (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72692857 linked to?
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
Does having rs72692857 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72692857 come from?
GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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