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Who was studied 341,805 European ancestry individuals, 6,006 African ancestry individuals, 7,316 South Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0488 lower (95% confidence interval 0.034-0.064); p = 2 × 10−10.
Where it sits Chromosome 1, band 1p31.3 — in an intron of PDE4B.
What each result means
A/ANo copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs72667426
What is rs72667426?
rs72667426 is a single position in the genome, in or near the PDE4B gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72667426 linked to?
On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.
Does having rs72667426 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72667426 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
C-reactive protein levels (rs72667426). MyGeneLog™. https://www.mygenelog.com/variants/rs72667426