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Back pain

C8orf34 · rs72666766

What the study found

Who was studied 119,384 European ancestry cases, 334,478 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0461 lower (95% confidence interval 0.034-0.058); p = 6 × 10−14.

How common The A allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 8, band 8q13.2 — in an intron of C8orf34.

What each result means

A/A Two copies of the version the research linked to Back pain. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Back pain. That is a smaller link than two copies.
G/G No copy of the version the research linked to Back pain. This is the starting point the study compared everyone against.
Source

Questions about rs72666766

What is rs72666766?

rs72666766 is a single position in the genome, in or near the C8orf34 gene. Published research associates it with back pain. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72666766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72666766 come from?

GWAS Catalog, Pain 2019, PMID:30747904. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Back pain (rs72666766). MyGeneLog™. https://www.mygenelog.com/variants/rs72666766

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