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CXCL11 protein levels

SCARB2 · rs72655528

Where this position leads

Condition: Celiac Disease

rs72655528 Condition: Celiac Disease Celiac Disease Condition rs72655528 rs72655528 SCARB2

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.181 lower (95% confidence interval 0.13-0.24); p = 4 × 10−12.

How common The A allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 4, band 4q21.1 — in an intron of SCARB2.

What each result means

A/A Two copies of the version the research linked to CXCL11 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to CXCL11 protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to CXCL11 protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs72655528

What is rs72655528?

rs72655528 is a single position in the genome, in or near the SCARB2 gene. Published research associates it with cxcl11 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72655528 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs72655528 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72655528 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

CXCL11 protein levels (rs72655528). MyGeneLog™. https://www.mygenelog.com/variants/rs72655528

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