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Myopia

ZMAT4 · rs72644322

Where this position leads

Condition: Myopia

rs72644322 Condition: Myopia Myopia Condition rs72644322 rs72644322 ZMAT4

What the study found

Who was studied 27,993 European ancestry cases, 36,275 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.135 lower (95% confidence interval 0.11-0.16); p = 4 × 10−19.

Where it sits Chromosome 8, band 8p11.21 — in an intron of ZMAT4.

What each result means

A/A Two copies of the version the research linked to Myopia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Myopia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Myopia. This is the starting point the study compared everyone against.
Source

Questions about rs72644322

What is rs72644322?

rs72644322 is a single position in the genome, in or near the ZMAT4 gene. Published research associates it with myopia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72644322 linked to?

On MyGeneLog this position is linked to Myopia. The research behind each link, and its sources, are set out on that condition page.

Does having rs72644322 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72644322 come from?

GWAS Catalog, EBioMedicine 2022, PMID:35841873. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Myopia (rs72644322). MyGeneLog™. https://www.mygenelog.com/variants/rs72644322

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