PRR5 · rs726170
Where this position leads
Condition: Bipolar Disorder
What the study found
Who was studied 398 European ancestry bipolar disorder cases, 1,231 European ancestry bipolar disorder controls.
The effect Each copy of the T allele carried 1.92 times the odds of Binge eating behaviour in bipolar disorder; p = 3 × 10−8.
How common The T allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 22, band 22q13.31 — in an intron of ARHGAP8.
rs726170 is a single position in the genome, in or near the PRR5 gene. Published research associates it with binge eating behaviour in bipolar disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Bipolar Disorder. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Transl Psychiatry 2018, PMID:29391396. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.