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Body fat percentage

PEPD · rs7258937

What the study found

Who was studied 442,278 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.016 % higher; p = 2 × 10−26.

How common The T allele had a frequency of about 51% in the people studied.

Where it sits Chromosome 19, band 19q13.11 — in an intron of PEPD.

What each result means

C/C No copy of the version the research linked to Body fat percentage. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body fat percentage. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body fat percentage. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7258937

What is rs7258937?

rs7258937 is a single position in the genome, in or near the PEPD gene. Published research associates it with body fat percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7258937 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7258937 come from?

GWAS Catalog, Diabetes 2021, PMID:33980691. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body fat percentage (rs7258937). MyGeneLog™. https://www.mygenelog.com/variants/rs7258937

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