Sensitive

Breast cancer

near UBA52P7 · rs725677

Where this position leads

Condition: Breast Cancer

rs725677 Condition: Breast Cancer Breast Cancer Condition rs725677 rs725677 near UBA52P7

What the study found

Who was studied 17,881 European ancestry female cases, 219,656 European ancestry female controls.

The effect The reported allele is C; the catalogue records no effect size ; p = 7 × 10−12.

Where it sits Chromosome 12, band 12q24.21 — between genes, 215.5 kb from UBA52P7.

What each result means

C/C Two copies of the version the research linked to Breast cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Breast cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Breast cancer. This is the starting point the study compared everyone against.
Source

Questions about rs725677

What is rs725677?

rs725677 is a single position in the genome, in or near the near UBA52P7 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs725677 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs725677 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs725677 come from?

GWAS Catalog, Nature communications 2020, PMID:32887889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Breast cancer (rs725677). MyGeneLog™. https://www.mygenelog.com/variants/rs725677

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