Sensitive

Coronary artery disease

MAP1S · rs7251815

Where this position leads

Condition: Coronary Artery Disease

rs7251815 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs7251815 rs7251815 MAP1S

What the study found

Who was studied up to 122,733 cases, up to 424,528 controls.

The effect Each copy of the T allele shifted the measure 0.0511 higher (95% confidence interval 0.038-0.065); p = 1 × 10−13.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 19, band 19p13.11 — in an intron of LOC124904649.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Coronary artery disease — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Coronary artery disease.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Coronary artery disease compared to the general population.
Source

Questions about rs7251815

What is rs7251815?

rs7251815 is a single position in the genome, in or near the MAP1S gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7251815 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7251815 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7251815 come from?

GWAS Catalog, Circ Res 2017, PMID:29212778. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease (rs7251815). MyGeneLog™. https://www.mygenelog.com/variants/rs7251815

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