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Apolipoprotein B levels

KANK2 · rs7249565

What the study found

Who was studied 439,214 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0145 lower (95% confidence interval 0.01-0.019); p = 3 × 10−12.

How common The G allele had a frequency of about 59% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — in an intron of KANK2.

What each result means

A/A No copy of the version the research linked to Apolipoprotein B levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Apolipoprotein B levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Apolipoprotein B levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7249565

What is rs7249565?

rs7249565 is a single position in the genome, in or near the KANK2 gene. Published research associates it with apolipoprotein b levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7249565 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7249565 come from?

GWAS Catalog, PLoS medicine 2020, PMID:32203549. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Apolipoprotein B levels (rs7249565). MyGeneLog™. https://www.mygenelog.com/variants/rs7249565

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