Standard

Body mass index

ZNF552 · rs72490768

Where this position leads

Condition: Childhood Body Mass Index

rs72490768 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs72490768 rs72490768 ZNF552

What the study found

Who was studied 507,850 East Asian ancestry individuals, 420,829 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0119 lower (95% confidence interval 0.0084-0.0154); p = 3 × 10−11.

Where it sits Chromosome 19, band 19q13.43 — in an intron of ZNF552.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72490768

What is rs72490768?

rs72490768 is a single position in the genome, in or near the ZNF552 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72490768 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs72490768 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72490768 come from?

GWAS Catalog, Nature communications 2025, PMID:40436827. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs72490768). MyGeneLog™. https://www.mygenelog.com/variants/rs72490768

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