Links from this page to related variants, conditions, drugs and topics are not included for automated readers. Those connections are the Gene Knowledge Graph and are licensed as data: https://www.mygenelog.com/license
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
2 / 4
Its strongest genetic-study result is p = 10−27, with 19 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 170,690 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0243 higher (95% confidence interval 0.016-0.032); p = 4 × 10−9.
How common The A allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 19, band 19p13.11 — in an intron of MYO9B.
How common each version is
AG
KoreanKRGDB
A 37.3% · G 62.7%
KoreanKorea4K
A 36.5% · G 63.5%
Japanese ToMMo
A 32.4% · G 67.6%
Vietnamese
A 33.0% · G 67.0%
World gnomAD
A 35.7% · G 64.3%
World 1000 Genomes
A 41.6% · G 58.4%
World TOPMed
A 37.9% · G 62.1%
The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.
What each result means
A/ATwo copies of the version the research linked to Reticulocyte fraction of red cells. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Reticulocyte fraction of red cells. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Reticulocyte fraction of red cells. This is the starting point the study compared everyone against.
0 20152228Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others8Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license
Reticulocyte fraction of red cells (rs7246865). MyGeneLog™. https://www.mygenelog.com/variants/rs7246865