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Epiretinal membrane

CPLX4 · rs7244528

What the study found

Who was studied 31,374 European ancestry cases, 414,052 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0898 lower (95% confidence interval 0.072-0.108); p = 3 × 10−22.

How common The A allele had a frequency of about 70% in the people studied.

Where it sits Chromosome 18, band 18q21.32 — inside CPLX4.

What each result means

A/A Two copies of the version the research linked to Epiretinal membrane. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Epiretinal membrane. That is a smaller link than two copies.
T/T No copy of the version the research linked to Epiretinal membrane. This is the starting point the study compared everyone against.
Source

Questions about rs7244528

What is rs7244528?

rs7244528 is a single position in the genome, in or near the CPLX4 gene. Published research associates it with epiretinal membrane. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7244528 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7244528 come from?

GWAS Catalog, Cell genomics 2024, PMID:38870908. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Epiretinal membrane (rs7244528). MyGeneLog™. https://www.mygenelog.com/variants/rs7244528

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