Sensitive

Lung cancer

GAREM1 · rs7243964

Where this position leads

Condition: Lung Cancer

rs7243964 Condition: Lung Cancer Lung Cancer Condition rs7243964 rs7243964 GAREM1

What the study found

Who was studied 59,774 European ancestry cases, 1,416,415 European ancestry controls, 11,773 East Asian ancestry cases, 288,419 East Asian ancestry controls, 4,782 African ancestry cases, 122,496 African ancestry controls, 624 Hispanic/Latino American ancestry cases, 59,042 Hispanic/Latino American ancestry controls.

The effect Each copy of the A allele shifted the measure 0.0731 higher (95% confidence interval 0.054-0.092); p = 3 × 10−14.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 18, band 18q12.1 — in an intron of GAREM1.

What each result means

A/A Two copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lung cancer. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.
Source

Questions about rs7243964

What is rs7243964?

rs7243964 is a single position in the genome, in or near the GAREM1 gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7243964 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs7243964 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7243964 come from?

GWAS Catalog, Nature communications 2026, PMID:42364979. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung cancer (rs7243964). MyGeneLog™. https://www.mygenelog.com/variants/rs7243964

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