0 1752217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 218,920 European ancestry cases, 725,213 European ancestry controls.
The effect
Each copy of the A allele carried 0.95 times the odds of Haemorrhoidal disease (95% confidence interval 0.94-0.96); p = 2 × 10−31.
How common The A allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 6, band 6p25.3 — in an intron of GMDS.
What each result means
A/ATwo copies of the version the research linked to Haemorrhoidal disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Haemorrhoidal disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Haemorrhoidal disease. This is the starting point the study compared everyone against.
rs722587 is a single position in the genome, in or near the GMDS gene. Published research associates it with haemorrhoidal disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs722587 linked to?
On MyGeneLog this position is linked to Haemorrhoidal Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs722587 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs722587 come from?
GWAS Catalog, Gut 2021, PMID:33888516. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1752217Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot5Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others7Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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