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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,347 Finnish ancestry cases, 270,964 Finnish ancestry controls.
The effect
Each copy of the C allele carried 0.89 times the odds of Lumbar disc herniation requiring surgery (95% confidence interval 0.86-0.93); p = 9 × 10−10.
How common The C allele had a frequency of about 31% in the people studied.
Where it sits Chromosome 17, band 17q24.3 — between genes, 106.6 kb from MYL6P5.
What each result means
A/ANo copy of the version the research linked to Lumbar disc herniation requiring surgery. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Lumbar disc herniation requiring surgery. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Lumbar disc herniation requiring surgery. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 39511132 · open access
Questions about rs7225015
What is rs7225015?
rs7225015 is a single position in the genome, in or near the near MYL6P5 gene. Published research associates it with lumbar disc herniation requiring surgery. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7225015 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7225015 come from?
GWAS Catalog, Nature communications 2024, PMID:39511132. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Lumbar disc herniation requiring surgery (rs7225015). MyGeneLog™. https://www.mygenelog.com/variants/rs7225015