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C-C motif chemokine 15 levels

near CCL23 · rs7221769

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 997 European ancestry individuals; replicated in 338 Greater Middle Eastern (Middle Eastern, North African or Persian), South Asian ancestry, Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 1.52 higher (95% confidence interval 1.39-1.65); p = 4 × 10⁻⁹³.

Where it sits Chromosome 17, band 17q12 — between genes, 5.6 kb from CCL23.

What each result means

C/C Two copies of the version the research linked to C-C motif chemokine 15 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.

C/T One copy of the version the research linked to C-C motif chemokine 15 levels. That is a smaller link than two copies.

T/T No copy of the version the research linked to C-C motif chemokine 15 levels. This is the starting point the study compared everyone against.

Source

Connecting genetic risk to disease end points through the human blood plasma proteome

Suhre K, Arnold M, Bhagwat AM, Cotton RJ, Engelke R, Raffler J, Sarwath H, Thareja G, Wahl A, DeLisle RK, Gold L, Pezer M

and 12 more — show all

Lauc G, El-Din Selim MA, Mook-Kanamori DO, Al-Dous EK, Mohamoud YA, Malek J, Strauch K, Grallert H, Peters A, Kastenmüller G, Gieger C, Graumann J

Nature communications · 2017 · PMID 28240269 · open access

Questions about rs7221769

What is rs7221769?

rs7221769 is a single position in the genome, in or near the near CCL23 gene. Published research associates it with c-c motif chemokine 15 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7221769 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7221769 come from?

GWAS Catalog, Nature communications 2017, PMID:28240269. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-C motif chemokine 15 levels (rs7221769). MyGeneLog™. https://www.mygenelog.com/variants/rs7221769

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