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Standard

Sweet food liking

near RGS9 · rs7221051

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−9, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 1,482 Italian ancestry individuals; replicated in 1,073 Italian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.322 lower (95% confidence interval 0.22-0.43); p = 1 × 10−9.

Where it sits Chromosome 17, band 17q24.1 — between genes, 17.9 kb from RGS9.

How common each version is

AG
Korean KRGDB
A 1.1% · G 98.9%
Korean Korea4K
A 0.8% · G 99.2%
Korean Korea1K
A 0.7% · G 99.3%
Japanese ToMMo
A 0.7% · G 99.4%
Vietnamese
A 2.3% · G 97.7%
World gnomAD
A 21.9% · G 78.1%
World 1000 Genomes
A 20.6% · G 79.4%
World TOPMed
A 23.1% · G 76.9%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

A/A Two copies of the version the research linked to Sweet food liking. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Sweet food liking. That is a smaller link than two copies.
G/G No copy of the version the research linked to Sweet food liking. This is the starting point the study compared everyone against.
Source

From our blog

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Sweet food liking (rs7221051). MyGeneLog™. https://www.mygenelog.com/variants/rs7221051

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