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Prostate-specific antigen levels

near LINC00670 · rs7219536

What the study found

Who was studied 85,824 European ancestry individuals, 3,509 African American or Afro-Caribbean individuals, 3,337 East Asian ancestry individuals, 3,098 Hispanic or Latin American individuals.

The effect Each copy of the T allele shifted the measure 0.025 higher (95% confidence interval 0.017-0.033); p = 6 × 10−12.

How common The T allele had a frequency of about 50% in the people studied.

Where it sits Chromosome 17, band 17p12 — between genes, 132.1 kb from LINC00670.

What each result means

C/C No copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7219536

What is rs7219536?

rs7219536 is a single position in the genome, in or near the near LINC00670 gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7219536 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7219536 come from?

GWAS Catalog, Nature medicine 2023, PMID:37264206. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Prostate-specific antigen levels (rs7219536). MyGeneLog™. https://www.mygenelog.com/variants/rs7219536

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