0 17122336Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others6Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 233 African ancestry cases, 122 Hispanic/Latino cases, 70 East Asian ancestry cases, 2,196 European ancestry cases, 138 South Asian ancestry cases, 21 cases, 1,331 African ancestry controls, 170 Hispanic/Latino controls, 333 East Asian ancestry controls, 42,902 European ancestry controls, 1,727 South Asian ancestry controls, 1,023 controls; replicated in 1,643 European or unknown ancestry cases, 6,628 European or unknown ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.22 lower (95% confidence interval 0.15-0.29); p = 7 × 10−10.
How common The G allele had a frequency of about 42% in the people studied.
Where it sits Chromosome 17, band 17q24.2 — in an intron of PRKCA.
What each result means
A/ANo copy of the version the research linked to Hypertrophic cardiomyopathy. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Hypertrophic cardiomyopathy. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Hypertrophic cardiomyopathy. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs7210446 is a single position in the genome, in or near the PRKCA gene. Published research associates it with hypertrophic cardiomyopathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7210446 linked to?
On MyGeneLog this position is linked to Hypertrophic Cardiomyopathy. The research behind each link, and its sources, are set out on that condition page.
Does having rs7210446 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7210446 come from?
GWAS Catalog, Nature genetics 2021, PMID:33495597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 17122336Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)3ByteDance (Doubao)3Others6Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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