Standard

Ulcerative colitis

near SLC39A11 · rs7210086

Where this position leads

Condition: Ulcerative Colitis

rs7210086 Condition: Ulcerative Colitis Ulcerative Colitis Condition rs7210086 rs7210086 near SLC39A11

What the study found

Who was studied Up to 12,924 European ancestry cases, up to 21,442 European ancestry controls; replicated in Up to 25,683 European ancestry cases, up to 17,015 European ancestry controls.

The effect Each copy of the A allele carried 1.11 times the odds of Ulcerative colitis (95% confidence interval 1.062-1.163); p = 2 × 10−9.

How common The A allele had a frequency of about 80% in the people studied.

Where it sits Chromosome 17, band 17q24.3 — between genes, 0.4 kb from SLC39A11.

What each result means

A/A Two copies of the version the research linked to Ulcerative colitis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Ulcerative colitis. That is a smaller link than two copies.
C/C No copy of the version the research linked to Ulcerative colitis. This is the starting point the study compared everyone against.
Source

Questions about rs7210086

What is rs7210086?

rs7210086 is a single position in the genome, in or near the near SLC39A11 gene. Published research associates it with ulcerative colitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7210086 linked to?

On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.

Does having rs7210086 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7210086 come from?

GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Ulcerative colitis (rs7210086). MyGeneLog™. https://www.mygenelog.com/variants/rs7210086

← See all variants