Sensitive

Systemic lupus erythematosus

CLEC16A · rs7206912

Where this position leads

Condition: Systemic Lupus Erythematosus

rs7206912 Condition: Systemic Lupus Erythematosus Systemic Lupus Erythematosus Condition rs7206912 rs7206912 CLEC16A

What the study found

Who was studied 16,491 European ancestry cases, 1,202,106 European ancestry controls, 5,051 East Asian ancestry cases, 185,362 East Asian ancestry controls, 740 African American or Afro-Caribbean cases, 120,993 African American or Afro-Caribbean controls, 212 Hispanic or Latin American cases, 59,641 Hispanic or Latin American controls.

The effect Each copy of the C allele shifted the measure 0.0921 lower (95% confidence interval 0.07-0.115); p = 1 × 10−12.

Where it sits Chromosome 16, band 16p13.13 — in an intron of CLEC16A.

What each result means

C/C Two copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/G No copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
Source

Questions about rs7206912

What is rs7206912?

rs7206912 is a single position in the genome, in or near the CLEC16A gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7206912 linked to?

On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.

Does having rs7206912 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7206912 come from?

GWAS Catalog, Mammalian genome : official journal of the International Mammalian Genome Society 2026, PMID:42581184. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systemic lupus erythematosus (rs7206912). MyGeneLog™. https://www.mygenelog.com/variants/rs7206912

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