A/APublished research associates this genotype with typical/baseline likelihood of Breast cancer — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:23535729)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Breast cancer. (GWAS Catalog, Nat Genet 2013, PMID:23535729)
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Breast cancer compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:23535729)
rs720475 is a single position in the genome, in or near the ARHGEF5 gene. Published research associates it with breast cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs720475 linked to?
On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.
Does having rs720475 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs720475 come from?
GWAS Catalog, Nat Genet 2013, PMID:23535729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.