Sensitive

Stroke

DYRK1A · rs720470

Where this position leads

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Stroke — no copies of the reported risk allele.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Stroke.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Stroke compared to the general population.

Source

Genome-wide meta-analysis identifies 3 novel loci associated with stroke

Malik R, Rannikmäe K, Traylor M, Georgakis MK, Sargurupremraj M, Markus HS, Hopewell JC, Debette S, Sudlow CLM, Dichgans M

MEGASTROKE consortium and the International Stroke Genetics Consortium

Annals of neurology · 2018 · PMID 30383316 · open access

Questions about rs720470

What is rs720470?

rs720470 is a single position in the genome, in or near the DYRK1A gene. Published research associates it with stroke. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs720470 linked to?

On MyGeneLog this position is linked to Ischaemic Stroke. The research behind each link, and its sources, are set out on that condition page.

Does having rs720470 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs720470 come from?

GWAS Catalog, Ann Neurol 2018, PMID:30383316. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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