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Who was studied 349,328 British ancestry individuals; replicated in 144,022 European ancestry,African ancestry,Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.02 higher (95% confidence interval 0.014-0.026); p = 2 × 10−11.
Where it sits Chromosome 16, band 16p12.3 — in an intron of UMOD.
What each result means
A/ANo copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs7203451 is a single position in the genome, in or near the UMOD gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7203451 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs7203451 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7203451 come from?
GWAS Catalog, Nature medicine 2024, PMID:38459180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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