Sensitive

Overall survival in breast cancer treated with Par-4 dependent chemotherapy

near UACA · rs720251

Where this position leads

Condition: Breast Cancer

rs720251 Condition: Breast Cancer Breast Cancer Condition rs720251 rs720251 near UACA

What the study found

Who was studied 949 European ancestry individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 4 × 10−9.

Where it sits Chromosome 15, band 15q23 — between genes, 8.4 kb from UACA.

What each result means

C/C No copy of the version the research linked to Overall survival in breast cancer treated with Par-4 dependent chemotherapy. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Overall survival in breast cancer treated with Par-4 dependent chemotherapy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Overall survival in breast cancer treated with Par-4 dependent chemotherapy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs720251

What is rs720251?

rs720251 is a single position in the genome, in or near the near UACA gene. Published research associates it with overall survival in breast cancer treated with par-4 dependent chemotherapy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs720251 linked to?

On MyGeneLog this position is linked to Breast Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs720251 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs720251 come from?

GWAS Catalog, NPJ breast cancer 2022, PMID:35322040. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Overall survival in breast cancer treated with Par-4 dependent chemotherapy (rs720251). MyGeneLog™. https://www.mygenelog.com/variants/rs720251

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