Sensitive
Pancreatic cancer
ZFP1 · rs7190458
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Pancreatic cancer compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Pancreatic cancer.
G/G
Published research associates this genotype with typical/baseline likelihood of Pancreatic cancer — no copies of the reported risk allele.
Source
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer
Wolpin BM,
Rizzato C,
Kraft P,
Kooperberg C,
Petersen GM,
Wang Z,
Arslan AA,
Beane-Freeman L,
Bracci PM,
Buring J,
Canzian F,
Duell EJ
and 106 more — show all
Gallinger S,
Giles GG,
Goodman GE,
Goodman PJ,
Jacobs EJ,
Kamineni A,
Klein AP,
Kolonel LN,
Kulke MH,
Li D,
Malats N,
Olson SH,
Risch HA,
Sesso HD,
Visvanathan K,
White E,
Zheng W,
Zheng W,
Abnet CC,
Albanes D,
Andreotti G,
Austin MA,
Barfield R,
Basso D,
Berndt SI,
Boutron-Ruault MC,
Brotzman M,
Büchler MW,
Bueno-de-Mesquita HB,
Bugert P,
Burdette L,
Campa D,
Caporaso NE,
Capurso G,
Chung C,
Cotterchio M,
Costello E,
Elena J,
Funel N,
Gaziano JM,
Giese NA,
Giovannucci EL,
Goggins M,
Gorman MJ,
Gross M,
Haiman CA,
Hassan M,
Helzlsouer KJ,
Henderson BE,
Holly EA,
Hu N,
Hunter DJ,
Innocenti F,
Jenab M,
Kaaks R,
Key TJ,
Khaw KT,
Klein EA,
Kogevinas M,
Krogh V,
Kupcinskas J,
Kurtz RC,
LaCroix A,
Landi MT,
Landi S,
Le Marchand L,
Mambrini A,
Mannisto S,
Milne RL,
Nakamura Y,
Oberg AL,
Owzar K,
Patel AV,
Peeters PH,
Peters U,
Pezzilli R,
Piepoli A,
Porta M,
Real FX,
Riboli E,
Rothman N,
Scarpa A,
Shu XO,
Silverman DT,
Soucek P,
Sund M,
Talar-Wojnarowska R,
Taylor PR,
Theodoropoulos GE,
Thornquist M,
Tjønneland A,
Tobias GS,
Trichopoulos D,
Vodicka P,
Wactawski-Wende J,
Wentzensen N,
Wu C,
Yu H,
Yu K,
Zeleniuch-Jacquotte A,
Hoover R,
Hartge P,
Fuchs C,
Chanock SJ,
Stolzenberg-Solomon RS,
Amundadottir LT
Nature genetics · 2014 · PMID 25086665 · open access
Questions about rs7190458
What is rs7190458?
rs7190458 is a single position in the genome, in or near the ZFP1 gene. Published research associates it with pancreatic cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7190458 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7190458 come from?
GWAS Catalog, Nat Genet 2014, PMID:25086665. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants