Sensitive

Graves' disease

near MAF · rs7190187

Where this position leads

Condition: Graves' Disease

rs7190187 Condition: Graves' Disease Graves' Disease Condition rs7190187 rs7190187 near MAF

What the study found

Who was studied 18,719 African ancestry, admixed American, East Asian ancestry, European ancestry, South Asian ancestry, Greater Middle Eastern cases, 2,441,938 African ancestry, admixed American, East Asian ancestry, European ancestry, South Asian ancestry, Greater Middle Eastern controls.

The effect Each copy of the T allele shifted the measure 0.143 higher (95% confidence interval 0.12-0.17); p = 7 × 10−35.

How common The T allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 16, band 16q23.2 — in an intron of MAFTRR.

What each result means

C/C No copy of the version the research linked to Graves' disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Graves' disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Graves' disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7190187

What is rs7190187?

rs7190187 is a single position in the genome, in or near the near MAF gene. Published research associates it with graves' disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7190187 linked to?

On MyGeneLog this position is linked to Graves' Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7190187 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7190187 come from?

GWAS Catalog, Nature genetics 2026, PMID:41644669. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Graves' disease (rs7190187). MyGeneLog™. https://www.mygenelog.com/variants/rs7190187

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