1 2412172227Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 172,332 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0347 lower (95% confidence interval 0.027-0.043); p = 8 × 10−18.
How common The C allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 15, band 15q22.31 — in an intron of DENND4A.
What each result means
C/CTwo copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
rs7181649 is a single position in the genome, in or near the DENND4A gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7181649 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs7181649 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7181649 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2412172227Reads by AI crawlersClaude1ChatGPT0Google · Gemini2Perplexity1Meta AI7Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total24Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Mean corpuscular hemoglobin (rs7181649). MyGeneLog™. https://www.mygenelog.com/variants/rs7181649