Sensitive

Coronary artery disease

AKAP13 · rs7177107

Where this position leads

Condition: Coronary Artery Disease

rs7177107 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs7177107 rs7177107 AKAP13

What the study found

Who was studied 190,493 European ancestry cases, 582,775 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 6 × 10−9.

Where it sits Chromosome 15, band 15q25.3 — a missense change in AKAP13.

What each result means

A/A Two copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
Source

Questions about rs7177107

What is rs7177107?

rs7177107 is a single position in the genome, in or near the AKAP13 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7177107 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7177107 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7177107 come from?

GWAS Catalog, Nature medicine 2022, PMID:35915156. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Coronary artery disease (rs7177107). MyGeneLog™. https://www.mygenelog.com/variants/rs7177107

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