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Platelet count

TCF12-DT · rs7175191

Where this position leads

Condition: Blood Cell Counts

rs7175191 Condition: Blood Cell Counts Blood Cell Counts Condition rs7175191 rs7175191 TCF12-DT

What the study found

Who was studied 721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−39.

How common The G allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 15, band 15q21.3 — in an intron of TCF12-DT.

What each result means

A/A No copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Platelet count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7175191

What is rs7175191?

rs7175191 is a single position in the genome, in or near the TCF12-DT gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7175191 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs7175191 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7175191 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count (rs7175191). MyGeneLog™. https://www.mygenelog.com/variants/rs7175191

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