1 2018227Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI8Microsoft · Copilot0Amazon2Apple2Others7Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 172,378 European ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0251 higher (95% confidence interval 0.018-0.033); p = 1 × 10−10.
How common The G allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 15, band 15q22.33 — in an intron of SMAD3.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Eosinophil percentage of white cells — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Eosinophil percentage of white cells.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Eosinophil percentage of white cells compared to the general population.
rs7174445 is a single position in the genome, in or near the SMAD3 gene. Published research associates it with eosinophil percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7174445 linked to?
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
Does having rs7174445 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7174445 come from?
GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 2018227Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI8Microsoft · Copilot0Amazon2Apple2Others7Total20Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Eosinophil percentage of white cells (rs7174445). MyGeneLog™. https://www.mygenelog.com/variants/rs7174445