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Blond vs. brown/black hair color

OCA2 · rs7170989

Where this position leads

Condition: Hair Color

rs7170989 Condition: Hair Color Hair Color Condition rs7170989 rs7170989 OCA2

What the study found

Who was studied 12,398 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.297 lower (95% confidence interval 0.2-0.39); p = 7 × 10−10.

Where it sits Chromosome 15, band 15q13.1 — in an intron of OCA2.

What each result means

C/C No copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7170989

What is rs7170989?

rs7170989 is a single position in the genome, in or near the OCA2 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7170989 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs7170989 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7170989 come from?

GWAS Catalog, Communications biology 2021, PMID:34737440. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Blond vs. brown/black hair color (rs7170989). MyGeneLog™. https://www.mygenelog.com/variants/rs7170989

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