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Developmental dysplasia of the hip

TRPM7 · rs7168702

What the study found

Who was studied 1,085 Japanese ancestry cases, 24,000 Japanese ancestry controls.

The effect Each copy of the T allele carried 0.20 times the odds of Developmental dysplasia of the hip (95% confidence interval 0.12-0.33); p = 8 × 10−10.

How common The T allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 15, band 15q21.2 — in an intron of TRPM7.

What each result means

C/C No copy of the version the research linked to Developmental dysplasia of the hip. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Developmental dysplasia of the hip. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Developmental dysplasia of the hip. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7168702

What is rs7168702?

rs7168702 is a single position in the genome, in or near the TRPM7 gene. Published research associates it with developmental dysplasia of the hip. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7168702 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7168702 come from?

GWAS Catalog, Bone research 2026, PMID:41912496. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Developmental dysplasia of the hip (rs7168702). MyGeneLog™. https://www.mygenelog.com/variants/rs7168702

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