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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 367 European ancestry cases, 31,563 European ancestry controls.
The effect
Each copy of the A allele carried 1.92 times the odds of Familial squamous cell lung carcinoma (95% confidence interval 1.55-2.37); p = 2 × 10−9.
How common The A allele had a frequency of about 14% in the people studied.
Where it sits Chromosome 4, band 4p15.31 — in an intron of LCORL.
What each result means
A/ATwo copies of the version the research linked to Familial squamous cell lung carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Familial squamous cell lung carcinoma. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Familial squamous cell lung carcinoma. This is the starting point the study compared everyone against.
rs71603396 is a single position in the genome, in or near the LCORL gene. Published research associates it with familial squamous cell lung carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs71603396 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs71603396 come from?
GWAS Catalog, Carcinogenesis 2018, PMID:29924316. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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