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Epilepsy and lamotrigine-induced maculopapular eruptions

HACE1 · rs71568191

Where this position leads

Condition: Epilepsy

rs71568191 Condition: Epilepsy Epilepsy Condition rs71568191 rs71568191 HACE1

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Epilepsy and lamotrigine-induced maculopapular eruptions compared to the general population. (GWAS Catalog, Epilepsy Res 2015, PMID:26220383)
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Epilepsy and lamotrigine-induced maculopapular eruptions. (GWAS Catalog, Epilepsy Res 2015, PMID:26220383)
G/G Published research associates this genotype with typical/baseline likelihood of Epilepsy and lamotrigine-induced maculopapular eruptions — no copies of the reported risk allele. (GWAS Catalog, Epilepsy Res 2015, PMID:26220383)
Source

Questions about rs71568191

What is rs71568191?

rs71568191 is a single position in the genome, in or near the HACE1 gene. Published research associates it with epilepsy and lamotrigine-induced maculopapular eruptions. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs71568191 linked to?

On MyGeneLog this position is linked to Epilepsy. The research behind each link, and its sources, are set out on that condition page.

Does having rs71568191 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs71568191 come from?

GWAS Catalog, Epilepsy Res 2015, PMID:26220383. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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