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Thyroid stimulating hormone levels

TSHR · rs7152963

What the study found

Who was studied 38,000 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.05 lower (95% confidence interval 0.036-0.064); p = 1 × 10−11.

Where it sits Chromosome 14, band 14q31.1 — in an intron of TSHR.

What each result means

A/A Two copies of the version the research linked to Thyroid stimulating hormone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Thyroid stimulating hormone levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Thyroid stimulating hormone levels. This is the starting point the study compared everyone against.
Source

Questions about rs7152963

What is rs7152963?

rs7152963 is a single position in the genome, in or near the TSHR gene. Published research associates it with thyroid stimulating hormone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7152963 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7152963 come from?

GWAS Catalog, Nature communications 2024, PMID:39414775. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels (rs7152963). MyGeneLog™. https://www.mygenelog.com/variants/rs7152963

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