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Platelet count

RAD51B · rs7151917

Where this position leads

Condition: Blood Cell Counts

rs7151917 Condition: Blood Cell Counts Blood Cell Counts Condition rs7151917 rs7151917 RAD51B

What the study found

Who was studied 350,474 European ancestry individuals, 148,623 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0404 lower (95% confidence interval 0.035-0.046); p = 1 × 10−42.

Where it sits Chromosome 14, band 14q24.1 — in an intron of RAD51B.

What each result means

G/G No copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Platelet count. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7151917

What is rs7151917?

rs7151917 is a single position in the genome, in or near the RAD51B gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7151917 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs7151917 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7151917 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count (rs7151917). MyGeneLog™. https://www.mygenelog.com/variants/rs7151917

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