Standard

Height (standard GWA)

LTBP2 · rs7148461

Where this position leads

Condition: Height

rs7148461 Condition: Height Height Condition rs7148461 rs7148461 LTBP2

What the study found

Who was studied 283,749 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.151 lower (95% confidence interval 0.12-0.19); p = 3 × 10−17.

Where it sits Chromosome 14, band 14q24.3 — in an intron of LTBP2.

What each result means

C/C Two copies of the version the research linked to Height (standard GWA). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height (standard GWA). That is a smaller link than two copies.
T/T No copy of the version the research linked to Height (standard GWA). This is the starting point the study compared everyone against.
Source

Questions about rs7148461

What is rs7148461?

rs7148461 is a single position in the genome, in or near the LTBP2 gene. Published research associates it with height (standard gwa). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7148461 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs7148461 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7148461 come from?

GWAS Catalog, Nature human behaviour 2023, PMID:37106081. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (standard GWA) (rs7148461). MyGeneLog™. https://www.mygenelog.com/variants/rs7148461

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