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Total lipid levels in large HDL

ZNF664 · rs71458830

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0303 lower (95% confidence interval 0.023-0.038); p = 2 × 10−15.

How common The C allele had a frequency of about 67% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — in an intron of ZNF664.

What each result means

C/C Two copies of the version the research linked to Total lipid levels in large HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Total lipid levels in large HDL. That is a smaller link than two copies.
T/T No copy of the version the research linked to Total lipid levels in large HDL. This is the starting point the study compared everyone against.
Source

Questions about rs71458830

What is rs71458830?

rs71458830 is a single position in the genome, in or near the ZNF664 gene. Published research associates it with total lipid levels in large hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs71458830 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs71458830 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total lipid levels in large HDL (rs71458830). MyGeneLog™. https://www.mygenelog.com/variants/rs71458830

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