Standard

Cholesterol, total

near TDRD15 · rs71435601

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Cholesterol, total — no copies of the reported risk allele.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesterol, total.

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesterol, total compared to the general population.

Source

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants

Nagy R, Boutin TS, Marten J, Huffman JE, Kerr SM, Campbell A, Evenden L, Gibson J, Amador C, Howard DM, Navarro P, Morris A

and 13 more — show all

Deary IJ, Hocking LJ, Padmanabhan S, Smith BH, Joshi P, Wilson JF, Hastie ND, Wright AF, McIntosh AM, Porteous DJ, Haley CS, Vitart V, Hayward C

Genome medicine · 2017 · PMID 28270201 · open access

Questions about rs71435601

What is rs71435601?

rs71435601 is a single position in the genome, in or near the near TDRD15 gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs71435601 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs71435601 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs71435601 come from?

GWAS Catalog, Genome Med 2017, PMID:28270201. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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