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Intracranial aneurysm

FGD6 · rs7137731

Where this position leads

Condition: Intracranial Aneurysm

rs7137731 Condition: Intracranial Aneurysm Intracranial Aneurysm Condition rs7137731 rs7137731 FGD6

What the study found

Who was studied 7,495 European ancestry cases, 3,259 East Asian ancestry cases, 71,934 European ancestry controls, 234,948 East Asian ancestry controls.

The effect Each copy of the T allele shifted the measure 0.119 lower (95% confidence interval 0.088-0.15); p = 5 × 10−14.

How common The T allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 12, band 12q22 — in an intron of FGD6.

What each result means

C/C No copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7137731

What is rs7137731?

rs7137731 is a single position in the genome, in or near the FGD6 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7137731 linked to?

On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.

Does having rs7137731 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7137731 come from?

GWAS Catalog, Nature genetics 2020, PMID:33199917. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Intracranial aneurysm (rs7137731). MyGeneLog™. https://www.mygenelog.com/variants/rs7137731

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