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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 70,548 African American or Afro-Caribbean individuals, 36,516 Hispanic or Latin American individuals, 3,839 East Asian ancestry individuals, 253,142 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0271 higher (95% confidence interval 0.021-0.034); p = 6 × 10−16.
How common The A allele had a frequency of about 64% in the people studied.
Where it sits Chromosome 22, band 22q12.2 — in an intron of ASCC2.
What each result means
A/ATwo copies of the version the research linked to lymphocyte (absolute count, maximum, inv-norm transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to lymphocyte (absolute count, maximum, inv-norm transformed). That is a smaller link than two copies.
G/GNo copy of the version the research linked to lymphocyte (absolute count, maximum, inv-norm transformed). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs713657
What is rs713657?
rs713657 is a single position in the genome, in or near the ASCC2 gene. Published research associates it with lymphocyte (absolute count, maximum, inv-norm transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs713657 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs713657 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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