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Standard

Height

FOLH1B · rs7130892

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10−7, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 455,180 Hispanic or Latin American individuals.

The effect Each copy of the C allele shifted the measure 0.0131 lower (95% confidence interval 0.0084-0.0178); p = 4 × 10−8.

How common The C allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 11, band 11q14.3 — in an intron of FOLH1B.

How common each version is

CT
Korean KRGDB
C 11.3% · T 88.7%
Korean Korea4K
C 10.5% · T 89.5%
Korean Korea1K
C 8.6% · T 91.4%
Japanese ToMMo
C 13.4% · T 86.6%
Vietnamese
C 9.9% · T 90.1%
World gnomAD
C 29.1% · T 70.9%
World 1000 Genomes
C 20.8% · T 79.2%
World TOPMed
C 28.3% · T 71.7%

The share of all copies of this position that are each version. Source: the population studies published in dbSNP (US NCBI); each row names its study.

What each result means

C/C Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Height. That is a smaller link than two copies.
T/T No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
Source

Quoting this page

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Height (rs7130892). MyGeneLog™. https://www.mygenelog.com/variants/rs7130892

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