Standard

Homocysteine levels

NOX4 · rs7130284

Where this position leads

Condition: Homocysteine Levels

rs7130284 Condition: Homocysteine Levels Homocysteine Levels Condition rs7130284 rs7130284 NOX4

What the study found

Who was studied 44,147 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.124 lower (95% confidence interval 0.099-0.15); p = 2 × 10−20.

How common The T allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 11, band 11q14.3 — in an intron of NOX4.

What each result means

C/C No copy of the version the research linked to Homocysteine levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Homocysteine levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Homocysteine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7130284

What is rs7130284?

rs7130284 is a single position in the genome, in or near the NOX4 gene. Published research associates it with homocysteine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7130284 linked to?

On MyGeneLog this position is linked to Homocysteine Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs7130284 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7130284 come from?

GWAS Catalog, Am J Clin Nutr 2013, PMID:23824729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Homocysteine levels (rs7130284). MyGeneLog™. https://www.mygenelog.com/variants/rs7130284

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