Standard

Systolic blood pressure

ADM · rs7129220

Where this position leads

Condition: Blood Pressure

rs7129220 Condition: Blood Pressure Blood Pressure Condition rs7129220 rs7129220 ADM

What the study found

Who was studied 69,395 European ancestry individuals; replicated in Up to 133,361 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.619 mmHg lower; p = 3 × 10−12.

How common The G allele had a frequency of about 89% in the people studied.

Where it sits Chromosome 11, band 11p15.4 — in an intron of CAND1.11.

What each result means

A/A No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7129220

What is rs7129220?

rs7129220 is a single position in the genome, in or near the ADM gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7129220 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs7129220?

Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7129220 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7129220 come from?

GWAS Catalog, Nature 2011, PMID:21909115. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs7129220). MyGeneLog™. https://www.mygenelog.com/variants/rs7129220

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