Sensitive

Prostate cancer

PRKCI · rs71277158

Where this position leads

Condition: Prostate Cancer

rs71277158 Condition: Prostate Cancer Prostate Cancer Condition rs71277158 rs71277158 PRKCI

What the study found

Who was studied 4,600 European ancestry cases, 2,941 European ancestry controls; replicated in 7,779 European ancestry cases, 7,623 European ancestry controls.

The effect Each copy of the T allele carried 1.22 times the odds of Prostate cancer (95% confidence interval 1.15-1.28); p = 8 × 10−14.

How common The T allele had a frequency of about 82% in the people studied.

Where it sits Chromosome 3, band 3q26.2 — in an intron of PRKCI.

What each result means

G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs71277158

What is rs71277158?

rs71277158 is a single position in the genome, in or near the PRKCI gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs71277158 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs71277158 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs71277158 come from?

GWAS Catalog, Nat Commun 2015, PMID:25939597. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs71277158). MyGeneLog™. https://www.mygenelog.com/variants/rs71277158

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