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Insomnia

ELP4 · rs7121536

Where this position leads

Condition: Insomnia

rs7121536 Condition: Insomnia Insomnia Condition rs7121536 rs7121536 ELP4

What the study found

Who was studied 390,751 European ancestry female cases, 1,018,386 European ancestry female controls.

The effect Each copy of the A allele shifted the measure 0.008 higher (95% confidence interval 0.006-0.01); p = 1 × 10−11.

Where it sits Chromosome 11, band 11p13 — in an intron of ELP4.

What each result means

A/A Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
Source

Questions about rs7121536

What is rs7121536?

rs7121536 is a single position in the genome, in or near the ELP4 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7121536 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs7121536 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7121536 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs7121536). MyGeneLog™. https://www.mygenelog.com/variants/rs7121536

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