Disruptive behavior disorder and attention deficit hyperactivity disorder
STIM1 · rs7118422
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,802 European ancestry cases, 31,305 European ancestry controls, 406 Han Chinese ancestry cases, 917 Han Chinese ancestry controls.
The effect
Each copy of the T allele carried 1.17 times the odds of Disruptive behavior disorder and attention deficit hyperactivity disorder (95% confidence interval 1.12-1.22); p = 3 × 10−10.
How common The T allele had a frequency of about 51% in the people studied.
Where it sits Chromosome 11, band 11p15.4 — in an intron of STIM1.
What each result means
C/CNo copy of the version the research linked to Disruptive behavior disorder and attention deficit hyperactivity disorder. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Disruptive behavior disorder and attention deficit hyperactivity disorder. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Disruptive behavior disorder and attention deficit hyperactivity disorder. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2021 · PMID 33495439 · open access
Questions about rs7118422
What is rs7118422?
rs7118422 is a single position in the genome, in or near the STIM1 gene. Published research associates it with disruptive behavior disorder and attention deficit hyperactivity disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7118422 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7118422 come from?
GWAS Catalog, Nature communications 2021, PMID:33495439. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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