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Vitamin D levels

COPB1 · rs7113429

Where this position leads

Condition: Gout

rs7113429 Condition: Gout Gout Condition rs7113429 rs7113429 COPB1

What the study found

Who was studied 327,435 European ancestry individuals, 5,845 African ancestry individuals, 6,425 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0488 higher (95% confidence interval 0.035-0.062); p = 2 × 10−12.

Where it sits Chromosome 11, band 11p15.2 — in an intron of COPB1.

What each result means

C/C Two copies of the version the research linked to Vitamin D levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Vitamin D levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Vitamin D levels. This is the starting point the study compared everyone against.
Source

Questions about rs7113429

What is rs7113429?

rs7113429 is a single position in the genome, in or near the COPB1 gene. Published research associates it with vitamin d levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7113429 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs7113429 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7113429 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vitamin D levels (rs7113429). MyGeneLog™. https://www.mygenelog.com/variants/rs7113429

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